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Chronic Neuropathic Pain

2025-09-23

Cause: Damage to or disease affecting the peripheral or central nervous system.

Mechanism: Damaged nerves send abnormal pain signals, even in the absence of a painful stimulus.

Pain characteristics: Burning, stinging, stabbing pain, tingling, numbness, and electric shock-like sensations.

Examples: Postherpetic neuralgia, painful post-traumatic trigeminal neuropathy, post-stroke pain, diabetic polyneuropathy, and sciatica.

Treatment: Antiepileptic medications (gabapentin, pregabalin), antidepressants (duloxetine, amitriptyline), sometimes nerve blocks, and physiotherapy.

Psychosomatic Pain

Cause: Psychological factors such as stress, anxiety, or depression that intensify or trigger real physical pain.

Mechanism: The body responds physically to psychological distress, for example through muscle tension, gastrointestinal disturbances, or headaches.

Pain characteristics: Highly variable, ranging from headaches, abdominal pain, and back pain to muscle pain. In many cases, no clear cause can be identified during diagnostic testing.

Examples: Tension-type headaches, irritable bowel syndrome, and neck pain associated with chronic stress.

Treatment: Psychotherapy, relaxation techniques, treatment of anxiety and depressive disorders, and pharmacological support when needed.

This content is intended for educational purposes only and does not replace professional medical advice.